Publications

Ksir, C. J., Hakan, R.L., Hall, J., and Kellar, K.J.    Nicotine exposure enhances behavioral stimulant effects of nicotine and increases [3H]acetylcholine binding to nicotinic  receptors.  Neuropharmacology, 24,  527-532, 1985.

Ksir, C.J.,  Hakan, R.L., and Kellar, K.J.   Chronic nicotine and locomotor activity: influences of exposure dose and test dose.   Psychopharmacology, 92,  25-29,  1987.

Hakan, R. L. and Ksir, C.J.    Nicotine-induced locomotor activity in  rats:  The role of  Pavlovian conditioning.    Pharmacology,Biochemistry and Behavior. Vol 29 (4), 661-667, 1988.

Hakan, R.L. and Henriksen, S.J.    Systemic opiate administration has heterogeneous effects on activity recorded from nucleus accumbens neurons in vivo.  Neuroscience Letters.  83: 307-312, 1987.

Hakan, R.L. and Henriksen, S.J.    Dopamine-dependent and dopamine-independent electrophysiological effects of opiates on single cell activity of the nucleus accumbens  septi in rats.  Journal of Neuroscience , 9(10): 3538-3546, 1989.

Hakan, R.L., Callaway, C. and Henriksen, S.J.   Electrophysiological Analysis of the neural  circuitry underlying opiate effects in the nucleus accumbens septi.  Neuroscience  Letters, 101: 163-168, 1989.

Callaway, C., Hakan, R.L. and Henriksen, S.J.   Distribution of amygdala input to the nucleus accumbens septi: An electrophysiological investigation. Journal of Neural Transmission, 83: 215-225, 1991.

Hakan, R.L., and Ksir, C.J.   Acute tolerance to the Locomotor stimulant effects of nicotine.  Psychopharmacology, 104 (3): 386-390, 1991 .

Hakan, R.L.,  Berg, G., and Henriksen, S.J.   Electrophysiological evidence for reciprocal connectivity between the nucleus accumbens septi and ventral pallidal region. Brain Research, 581: 344-350, 1992 .

Hakan, R.L., Hart, C. and Eyl, C.    Specific effects of systemic nicotine on neuronal activity in the nucleus accumbens septi. Synapse: 15: 191-197, 1993

Hakan, R.L., Henriksen, S.J.  and Eyl., C    Neuropharmacology of the nucleus accumbens:  Systemic morphine effects on single-unit responses evoked by ventral pallidum stimulation.  Neuroscience 63 (1): 85-93, 1994.

Hakan, R.L., and Eyl, C. .   Neuropharmacology of the nucleus accumbens: Iontophoretic application of morphine and nicotine have contrasting effects on single-unit responses evoked by ventral pallidum and fimbria stimulation.  Synapse 20; (2) 175-184, 1995.

Hakan, R.L.    Endogenous opioid inhibition of single-unit responses to  fimbria stimulation in the nucleus accumbens.   SYNAPSE, 2002

Non refereed Publications

Hakan, R.L., and Ksir, K.J.   Cocaine exposure increases subsequent behavioral response to nicotine.  Society for Neuroscience Abstracts, vol. 11: 1985.

Scratchley, D.A., Hakan, R.L., and Ksir, C.J.   Nicotine behavioral effects in a fish, Pimephales Promelas (fathead minnow).   Society for Neuroscience  Abstracts.  vol. 11:  1985.

Hakan, R.L., and Ksir, C.J.   Acute tolerance to the locomotor stimulant effects of nicotine: an indicator of receptor desensitization?   Society for Neuroscience  Abstracts.  12: 250.12, 1986

Hakan, R.L., and Henriksen, S.J.   Heterogeneous effects of opiate drugs on neurons recorded from the nucleus accumbens septi.     Society for Neuroscience  Abstracts.  13: 356.18, 1987

Hakan, R.L. and Henriksen, S.J. Electrophysiological effects of opiates on nucleus accumbens (NAS): Dopamine (DA) and other afferent influences.   Society for Neuroscience Abstracts, 14: 116.11,  1988

Hakan,  R.L., Berg, G. , and Henriksen, S.J.   Electrophysiological evidence for reciprocal and topographic projections between the nucleus accumbens (NAS) and ventral pallidum (VP).  Society for Neuroscience  Abstracts, 15: 1989.

Hakan,  R.L.,  Electrophysiological identification of accumbens (NAS) neurons be evoked responses to multiple afferent stimulation explains variance of NAS opioid drug effects.   Society for Neuroscience  Abstracts,  16: 382.14, 1990.

Peuster, A., Overman, W.H., Caulfield, S., and Hakan, R.L.   Radial arm maze measures development of spatial memory in young children.  Society for Neuroscience  Abstracts, 17: 414.4, 1991.

Hart, C., Strauss, A., and Hakan,  R.L.,    Neurophysiological effects of systemic nicotine on neurons in the nucleus accumbens.  Society for Neuroscience  Abstracts, 18: 229.2, 1992.

Eyl, C., and Hakan,  R.L.,  Specific effects of morphine and nicotine on neuronal responses to ventral pallidum and fimbria stimulation in the nucleus accumbens.  Society for Neuroscience  Abstracts, 19: 417.3, 1993.

Eyl, C., and Hakan,  R.L.,  Unique patterns of morphine and nicotine effects on evoked responses in the nucleus accumbens. Society for Neuroscience  Abstracts, 20:  1994

Pringle, G. and Hakan, R.L.   Opiate inhibition of projection neurons of the Ventral Subiculum.   SFNS Abstract  859.13, 1999

Pringle, G.J., and Hakan, R.L. (1998) "Systemic Morphine Inhibits the Subiculo-Accumbens Pathway." Symposium on Neuroscience Research at East Carolina University.

Reynolds, B. and Hakan, R.L.  (1998) Role of the Nucleus Accumbens in Spatially Learned Behavior."  Carolinas Psychology Conference