Wang

Wang Research Group @ UNC Wilmington

List of Publications

  1. M. J. Scannell, M. W. Hyatt, I. L. Budyak, M. A. Woldeyes, Y. Wang, "Revisit PEG-Induced Precipitation Assay for Protein Solubility Assessment of Monoclonal Antibody Formulations"Pharmaceutical Research, PMID: 34647231 (2021).[PDF]
  2. Y. Wang, R. F. Latypov, "Quantitative Evaluation of Protein Solubility in Aqueous Solutions by PEG-Induced Liquid-Liquid Phase Separation"Methods in Molecular Biology, 2039, 39-49 (2019).[PDF]
  3. J.B. Rowe, R.P. Flynn, H.R. Wooten, H.A. Noufer, R.A. Cancel, J. Zhang, J.A. Subramony, S. Pechenov, Y. Wang, "Submicron Aggregation of Chemically Denatured Monoclonal Antibody"Molecular Pharmaceutics, 15, 4710-4721 (2018).[PDF]
  4. J.B. Rowe, R.A. Cancel, T.D. Evangelous, R.P. Flynn, S. Pechenov, J.A. Subramony, J. Zhang, Y. Wang, "Meta-stability Gap in the Phase Diagram of Monoclonal IgG Antibody"Biophysical Journal, 113, 1750-1756 (2017).[PDF]
  5. Y. Wang, A. Lomakin, S. Kanai, R. Alex, G. B. Benedek, "Liquid−Liquid Phase Separation in Oligomeric Peptide Solutions."Langmuir, 33, 7715-7721 (2017).[PDF]
  6. G. Sun, Y. Wang, A. Lomakin, G. B. Benedek, H. E. Stanley, L. Xu, S. V. Buldyrev "The Phase Behavior Study of Human Antibody Solution Using Multi-scale Modeling"The Journal of Chemical Physics,145, 194901 (2016).[PDF]
  7. R.W. Thompson, R.F. Latypov, Y. Wang, A. Lomakin, J.A. Meyer, S. Vunnum, G. B. Benedek, "Evaluation of effects of pH and ionic strength on colloidal stability of IgG solutions by PEG-induced liquid-liquid phase separation."The Journal of Chemical Physics,145, 185101 (2016).[PDF]
  8. Y. Wang, A. Lomakin, S. Kanai, R. Alex, S. Belli, M. Donzelli, G. B. Benedek, "The molecular basis for the prolonged blood circulation of lipidated incretin peptides: peptide oligomerization or binding to serum albumin?"Journal of Controlled Release,241, 25-33 (2016).[link, free access by Nov.5]
  9. M.A. Kreutzberger, E. Tejada, Y. Wang, P.F. Almeida, "GUVs melt like LUVs: the large heat capacity of MLVs is not due to large size or small curvature."Biophysical Journal,12(2), 411-419 (2015).[PDF]
  10. Y. Wang, A. Lomakin, S. Kanai, R. Alex, G.B. Benedek, "Transformation of oligomers of lipidated peptide Induced by Change in pH."Molecular Pharmaceutics,12(2), 411-419 (2015).[PDF]
  11. Y. Wang, R.F. Latypov, A. Lomakin, J.A. Meyer, B.A. Kerwin, S. Vunnum, G.B. Benedek, "Quantitative evaluation of colloidal stability of antibody solutions using PEG-induced liquid-liquid phase separation."Molecular Pharmaceutics,11(5), 1391-1402 (2014).[PDF]
  12. Y. Wang, A. Lomakin, R.F. Latypov, J.P. Laubach, T. Hideshima, P.G. Richardson, N.C. Munshi, K.C. Anderson, G.B. Benedek, "Phase transitions in human IgG solutions."J. Chem. Phys.,139, 121904(1-9) (2013).[PDF]
  13. Y. Wang, A. Lomakin, T. Hideshima, J.P. Laubach, O.O. Ogun, P.G. Richardson, N.C. Munshi, K.C. Anderson, G.B. Benedek, "Pathological crystallization of human immunoglobulins."Proc. Natl. Acad.Sci. USA, 109, 13359–13361(2012).[PDF]
  14. Y. Wang, A. Lomakin, R.F. Latypov, G.B. Benedek, "Phase separation in solutions of monoclonal antibodies and the effect of human serum albumin" Proc. Natl. Acad.Sci. USA, 108, 16606–16611 (2011).[PDF]
  15. Y. Wang, A. Lomakin, J.J. McManus, O. Ogun, G.B. Benedek, "Phase behavior of mixtures of human lens proteins Gamma D and Beta B1" Proc. Natl. Acad.Sci. USA, 107, 13282–13287 (2010). [PDF]
  16. O. Annunziata, A. Payne and Y. Wang, “Solubility of lysozyme in the presence of aqueous chloride salts: common-ion effect and its role on solubility and crystal thermodynamics.”, J. Am. Chem. Soc., 130, 13347-13352 (2008). [PDF]
  17. Y. Wang and O. Annunziata, “Liquid-liquid phase transition of protein aqueous solutions isothermally induced by protein crosslinking”, Langmuir, 24, 2799-2807 (2008).[PDF]
  18. Y. Wang and O. Annunziata, “Comparison between protein-PEG interactions and the effect of PEG on protein-protein interactions using the liquid-liquid phase transition”, J. Phys. Chem. B, 111, 1222-1230 (2007).[PDF]