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For information about joining the ABC Lab, contact Dr. Mark Galizio or Dr. Kate Bruce. |
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A major focus in our laboratory has been the analysis of drug effects on recognition memory performance in rats using the Odor Span Task (OST). The OST is essentially an incrementing nonmatch-to-sample procedure that permits the assessment of accuracy as a function of the number of odor stimuli to remember. We have found that NMDA receptor antagonists amd benzodiazepines produced selective impairments in OST performance, but that other drugs, such as morphine, scopolamine, and psychomotor stimulants did not (Galizio, Deal, Hawkey & April, 2013; Hawkey, April & Galizio, 2014; MacQueen, Bullard & Galizio, 2011). Current research using this procedure is exploring the effects of additional drugs (e.g., GABA-A subtype selective compounds) and also the effects of non-pharmacological variables (e.g., number of comparison stimuli, retention interval) on OST performance. |
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